• Doç. Dr. OZAN ŞEN

Miracle Hormone Increasing After Gastric Sleeve Surgery: GLP-1

The name of this miracle hormone is GLP-1 , with its clear name Glucagon-like peptide-1. This hormone is mainly secreted from the L cells of the small intestine. A small amount is also secreted from the brain and pancreatic cells. This hormone is a hormone that controls satiety and appetite.

After gastric sleeve surgery, the secretion of this hormone from intestinal cells increases. This hormone shows its main beneficial effect on pancreatic tissue. The main problem, especially in diabetes, is the fatigue and destruction of the insulin-secreting cells in the pancreas. Therefore, in the later stages of diabetes, the pancreas cannot secrete enough insulin. The hormone GLP-1 miraculously ensures the regeneration of insulin-secreting cells in the pancreas. This hormone almost improves the pancreatic tissue.

The target of drugs used to lose weight lately is this GLP-1 hormone. Needle therapy (liraglutide), which is used as daily injections especially for weight loss, increases the secretion of GLP-1 in the body and cuts the appetite. It does this by directly acting on the appetite center in the brain. In addition, this hormone has a therapeutic effect in diabetes by lowering blood sugar.

Gastric sleeve surgery is not just a weight-loss surgery . It is also a surgery that eliminates diabetes and cures it. Here, sleeve gastrectomy shows this effect mostly through this hormone called GLP-1. GLP-1 is also secreted from a certain region in the brain and affects brain functions in a good way. Studies have shown that this hormone has a protective and healing effect in Alzheimer's disease, Parkinson's and cerebral palsy.

In summary, as seen in the table, GLP-1 hormone also increases energy metabolism. It lowers the cholesterol level in the body and contributes to weight loss by accelerating fat breakdown, namely lipolysis.

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